The role of lncRNA in the pathogenesis of chronic obstructive pulmonary disease.

Chronic obstructive pulmonary disease (COPD) is characterized by progressive and irreversible airflow obstruction with abnormal lung function. Because its pathogenesis involves multiple aspects of oxidative stress, immunity and inflammation, apoptosis, airway and lung repair and destruction, the clinical approach to COPD treatment is not further updated. Therefore, it is crucial to discover a new means of COPD diagnosis and treatment. COPD etiology is associated with complex interactions between environmental and genetic determinants. Numerous genes are involved in the pathogenic process of this illness in research samples exposed to hazardous environmental conditions. Among them, Long non-coding RNAs (lncRNAs) have been reported to be involved in the molecular mechanisms of COPD development induced by different environmental exposures and genetic susceptibility encounters, and some potential lncRNA biomarkers have been identified as early diagnostic, disease course determination, and therapeutic targets for COPD. In this review, we summarize the expression profiles of the reported lncRNAs that have been reported in COPD studies related to environmental risk factors such as smoking and air pollution exposure and provided an overview of the roles of those lncRNAs in the pathogenesis of the disease.

Microscopic and endoscopic "chopstick" technique removal of choroid plexus papilloma in the third ventricle of an infant: a case report with systematic review of literature.

Background: Choroid plexus papilloma (CPP) is rare and even rarer in infants and young children, and it usually occurs in the ventricles. Due to the physical peculiarities of infants, tumor removal by microscopic or endoscopic surgery alone is difficult. Case Presentation: A 3-month-old patient was found to have an abnormally enlarged head circumference for 7 days. Cranial magnetic resonance imaging (MRI) examination revealed a lesion in the third ventricle. The patient underwent combined microscopic and endoscopic "chopstick" technique to remove the tumor. He recovered well after the surgery. Postoperative pathological examination revealed CPP. Postoperative MRI suggested total resection of the tumor. Follow-up for 1 month showed no recurrence or distant metastasis. Conclusions: Combined microscopic and endoscopic "chopstick" technique may be a suitable approach to remove tumors in infant ventricles.

Research on Improving the Executive Ability of University Administrators Based on Deep Learning.

Over the years, experts have focused their research on ways to increase the executive capacity of university administrators. This is because only by improving the quality of execution of college and university administrative personnel can they actively execute various policies and measures, fully exploit their subjective initiative, and ensure the educational reform of colleges and universities. Increasing the executive capacity of administrative staff can help colleges and universities manage more effectively. Therefore, in the development process of higher education institutions, it is necessary to strengthen the execution of administrative staff, especially the need to adhere to the problem as the basic orientation. Take scientific and practical steps to strengthen administrative personnel's executive ability in light of current issues with administrative management personnel's executive power, and establish the groundwork for ensuring the quality of management work. Combining deep learning, this paper proposes a path to improve the executive power of college administrators based on deep learning. To begin, familiarize yourself with the deep noise reduction autoencoder model and support vector regression (SVR) theory and build the DDAE-SVR deep neural network (DNN) model. Then, input a small-scale feature index sample data set and a large-scale short-term traffic flow data set for experiments; then, assess the model's parameters to achieve the optimal model. Finally, use performance indicators such as MSE and MAPE to compare with other shallow models to verify the effectiveness and advantages of the DDAE-SVR DNN model in the execution improvement path output of university administrators and large-scale data sets.

Electrochemical Performance of Sb4O5Cl2 as a New Anode Material in Aqueous Chloride-Ion Battery.

Chloride-ion battery is considered as the promising electrochemical system due to its high energy density in theory. However, aqueous chloride-ion redox materials are limitedly reported owing to their instability or dissolution in aqueous electrolyte. Here, we synthetize a new electrochemical chloride-ion material, Sb4O5Cl2, investigate its electrochemical performance in aqueous NaCl electrolyte, and assemble into aqueous chloride-ion battery with silver as cathode. During the battery charge process, Sb4O5Cl2 anode electrochemically releases chloride ions, which are captured by Ag cathode with the formation of silver chloride while the discharging reverses the process. The battery demonstrates favorable electrochemical performance. With current density of 600 mA g-1, the battery discharge capacity of 34.6 mAh g-1 can be maintained for 50 cycles. This work is greatly significant for the development of anion electrochemical energy storage.